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murine anti nuclear antibody igg elisa kit  (Cusabio)


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    Cusabio murine anti nuclear antibody igg elisa kit
    GPR183 antagonism suppresses nephritis severity, plasmablast differentiation, and autoantibody production in female mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 17) female mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 11) compared to controls ( n = 13) female mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 14) and control ( n = 18) female mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 14) and control ( n = 17) female mice with lupus nephritis. (E) Summary dot plot shows the abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) female mice with lupus nephritis. (F) Summary dot plot shows the abundance <t>of</t> <t>anti-nuclear</t> antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 14) female mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.
    Murine Anti Nuclear Antibody Igg Elisa Kit, supplied by Cusabio, used in various techniques. Bioz Stars score: 93/100, based on 25 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/murine anti nuclear antibody igg elisa kit/product/Cusabio
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    murine anti nuclear antibody igg elisa kit - by Bioz Stars, 2026-05
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    Images

    1) Product Images from "Sexual dimorphism of early GPR183-dependent B cell responses in systemic lupus erythematosus"

    Article Title: Sexual dimorphism of early GPR183-dependent B cell responses in systemic lupus erythematosus

    Journal: iScience

    doi: 10.1016/j.isci.2026.114980

    GPR183 antagonism suppresses nephritis severity, plasmablast differentiation, and autoantibody production in female mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 17) female mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 11) compared to controls ( n = 13) female mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 14) and control ( n = 18) female mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 14) and control ( n = 17) female mice with lupus nephritis. (E) Summary dot plot shows the abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) female mice with lupus nephritis. (F) Summary dot plot shows the abundance of anti-nuclear antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 14) female mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.
    Figure Legend Snippet: GPR183 antagonism suppresses nephritis severity, plasmablast differentiation, and autoantibody production in female mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 17) female mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 11) compared to controls ( n = 13) female mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 14) and control ( n = 18) female mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 14) and control ( n = 17) female mice with lupus nephritis. (E) Summary dot plot shows the abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) female mice with lupus nephritis. (F) Summary dot plot shows the abundance of anti-nuclear antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 14) female mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.

    Techniques Used: Control, Flow Cytometry, MANN-WHITNEY

    GPR183 antagonism does not suppress nephritis severity, plasmablast differentiation, and autoantibody production in male mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 23) male mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 9) compared to controls ( n = 14) male mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 11) and control ( n = 17) male mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 13) and control ( n = 20) male mice with lupus nephritis. (E) Summary dot plot shows abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) male mice with lupus nephritis. (F) Summary dot plot shows abundance of anti-nuclear antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 18) male mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.
    Figure Legend Snippet: GPR183 antagonism does not suppress nephritis severity, plasmablast differentiation, and autoantibody production in male mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 23) male mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 9) compared to controls ( n = 14) male mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 11) and control ( n = 17) male mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 13) and control ( n = 20) male mice with lupus nephritis. (E) Summary dot plot shows abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) male mice with lupus nephritis. (F) Summary dot plot shows abundance of anti-nuclear antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 18) male mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.

    Techniques Used: Control, Flow Cytometry, MANN-WHITNEY



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    GPR183 antagonism suppresses nephritis severity, plasmablast differentiation, and autoantibody production in female mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 17) female mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 11) compared to controls ( n = 13) female mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 14) and control ( n = 18) female mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 14) and control ( n = 17) female mice with lupus nephritis. (E) Summary dot plot shows the abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) female mice with lupus nephritis. (F) Summary dot plot shows the abundance <t>of</t> <t>anti-nuclear</t> antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 14) female mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.
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    Image Search Results


    GPR183 antagonism suppresses nephritis severity, plasmablast differentiation, and autoantibody production in female mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 17) female mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 11) compared to controls ( n = 13) female mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 14) and control ( n = 18) female mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 14) and control ( n = 17) female mice with lupus nephritis. (E) Summary dot plot shows the abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) female mice with lupus nephritis. (F) Summary dot plot shows the abundance of anti-nuclear antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 14) female mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.

    Journal: iScience

    Article Title: Sexual dimorphism of early GPR183-dependent B cell responses in systemic lupus erythematosus

    doi: 10.1016/j.isci.2026.114980

    Figure Lengend Snippet: GPR183 antagonism suppresses nephritis severity, plasmablast differentiation, and autoantibody production in female mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 17) female mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 11) compared to controls ( n = 13) female mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 14) and control ( n = 18) female mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 14) and control ( n = 17) female mice with lupus nephritis. (E) Summary dot plot shows the abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) female mice with lupus nephritis. (F) Summary dot plot shows the abundance of anti-nuclear antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 14) female mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.

    Article Snippet: Murine anti-nuclear antibody (IgG) ELISA kit , Cusabio , Cat# CSB-E12912m.

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    GPR183 antagonism does not suppress nephritis severity, plasmablast differentiation, and autoantibody production in male mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 23) male mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 9) compared to controls ( n = 14) male mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 11) and control ( n = 17) male mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 13) and control ( n = 20) male mice with lupus nephritis. (E) Summary dot plot shows abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) male mice with lupus nephritis. (F) Summary dot plot shows abundance of anti-nuclear antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 18) male mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.

    Journal: iScience

    Article Title: Sexual dimorphism of early GPR183-dependent B cell responses in systemic lupus erythematosus

    doi: 10.1016/j.isci.2026.114980

    Figure Lengend Snippet: GPR183 antagonism does not suppress nephritis severity, plasmablast differentiation, and autoantibody production in male mice (A) Line graph shows urine proteinuria score in NIBR189-treated ( n = 14) compared to control ( n = 23) male mice with lupus nephritis. (B) Representative images (left, scale bar = 100 μm) and summary dot plot (right) show histological scoring of kidney pathology in NIBR189-treated ( n = 9) compared to controls ( n = 14) male mice with lupus nephritis. (C) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of splenic CD19 + CD95 + GL7 + Germinal Center (GC) B cells in NIBR189-treated ( n = 11) and control ( n = 17) male mice with lupus nephritis. (D) Representative flow cytometry plots (left) and summary dot plot (right) show the percentage of CD19 + CD138 + Blimp-1 + plasmablasts in NIBR189-treated ( n = 13) and control ( n = 20) male mice with lupus nephritis. (E) Summary dot plot shows abundance of total IgG (μg/mL) in the sera of NIBR189-treated ( n = 7) and control ( n = 8) male mice with lupus nephritis. (F) Summary dot plot shows abundance of anti-nuclear antibodies (μg/mL) in the sera of NIBR189-treated ( n = 11) and control ( n = 18) male mice with lupus nephritis. Lines in line graphs and dot plots represent mean ± SEM. Cumulative data of at least 3 independent experiments is shown. A two-way ANOVA test and B–F Mann-Whitney test were used to determine the significance of the difference between groups.

    Article Snippet: Murine anti-nuclear antibody (IgG) ELISA kit , Cusabio , Cat# CSB-E12912m.

    Techniques: Control, Flow Cytometry, MANN-WHITNEY